Patients with growth hormone deficiency associated with intracranial lesions should undergo regular examinations for progression or relapse of the disease.
The vermittels-protocol Serie (PPS) welches a subset of the FAS that included all subjects without any major protocol deviations. The FAS was the main data set for the evaluation of efficacy. Both ITT and PPS were analyzed to prevent selection bias. Safety data analyses were performed on a safety Satz (SS) that included all subjects World health organization had received the study drug at least once in the treatment group and all subjects in the control group after randomization.
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Additional benefits include a small number of side effects. Unwanted side effects occur when you change the dosage and the schedule of injections (in the vast majority of cases). It is worth remembering that long-term Jintropin therapy can lead to hypothyroidism.
Figure 6 shows representative images of CP tissue stained with an antibody against Ki-67. There are only a few positive cells (+) or no positive cells (−) hinein the brain CP tissue of cynomolgus monkeys in most animals, except for one animal in the 3 mg/kg/week group, which had multiple positive cells in the CP(++).
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A functional observational battery (FOB) of neurobehavioral assessments welches conducted to detect any neurobehavioral deficits resulting from potential CP dysfunction, including home cage observations, out-of-cage observations, and open field activity assessments hinein animals of both control and animals treated with 0.
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Those alterations were quite slight/minor and recoverable, which indicates that they had no significant effect on cell viability and function.
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